Inline monitoring of SLES and glycerin in cosmetics and detergents
How inline Raman measurement stabilizes the production of SLES, glycerin, and surfactant blends in cosmetics and detergents — from the sulfate band to the PLS model in Spectrally OS.
Category: Process chemistry
SPAD Detectors in Process Raman Spectroscopy
SPAD CMOS matrices and time-gated Raman as a pathway for eliminating fluorescence background — a review of recent publications and context for process analyzers.
PAT Beyond Pharmaceuticals — A Guide for Specialty Chemistry
Process Analytical Technology (PAT) is increasingly moving beyond pharmaceuticals — in specialty chemicals, PAT shortens cycles, reduces rework, and delivers a hard ROI in 6–10 months. A guide to selecting techniques, implementation architecture, and maintaining chemometric models.
PAT Beyond Pharmaceuticals — A Guide for Specialty Chemistry
PAT (Process Analytical Technology) originated in pharmaceuticals, but today its largest field of application is specialty chemistry. A guide to the layers of the PAT stack, technique selection, implementation challenges, and the Gekko Photonics offering — Spectrally X1 INLINE, LAB, PORTABLE, and Spectrally OS.
Multi-probe Raman analyzer — when and how to design
Guide to multi-probe architectures in process Raman — when it is worthwhile, what options are available (time-division multiplexing, spatial multiplexing, distributed configuration), and what to consider when designing with multiple measurement points.
PAT and QbD Regulations 2026 — What's New in Pharmacy and Chemistry
The first quarter of 2026 brought an agreement on the EU Pharma Package, joint FDA/EMA guidelines for AI in pharmaceuticals, finalization of Annex 22, and a full year of compliance with the new Annex 1. What this means for PAT/QbD teams in pharmaceuticals and chemistry.
Laboratory vs. Process Raman Spectrometer — Key Differences
What realistically distinguishes laboratory Raman spectroscopy from process Raman spectroscopy: architecture, measurement accessibility, calibration, integration with DCS, and the financial model. A comparison from the perspective of a Polish manufacturer.
Monitoring of free phenol and formaldehyde in PF resins
Continuous monitoring of free phenol and formaldehyde in a PF resin reactor via inline Raman spectroscopy — how it eliminates analytical delay, reduces operator exposure, and enables real-time control of the condensation endpoint.