SPAD Detectors in Raman Spectroscopy — A 2026 Overview

CMOS-SPAD Arrays Return to the Fore as a Direction for Fluorescence Suppression in Process Raman. A Review of 2025–2026 Publications and What It Means for Inline Implementations.
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CMOS-SPAD Arrays Return to the Fore as a Direction for Fluorescence Suppression in Process Raman. A Review of 2025–2026 Publications and What It Means for Inline Implementations.

How inline Raman measurement stabilizes the production of SLES, glycerin, and surfactant blends in cosmetics and detergents — from the sulfate band to the PLS model in Spectrally OS.

PITTCON, IFPAC, ICORS, SCIX, ACHEMA — an overview of the key Raman and PAT conferences in 2026 from a process engineer's perspective.

Guide to multi-probe architectures in process Raman — when it is worthwhile, what options are available (time-division multiplexing, spatial multiplexing, distributed configuration), and what to consider when designing with multiple measurement points.

The first quarter of 2026 brought an agreement on the EU Pharma Package, joint FDA/EMA guidelines for AI in pharmaceuticals, finalization of Annex 22, and a full year of compliance with the new Annex 1. What this means for PAT/QbD teams in pharmaceuticals and chemistry.

What realistically distinguishes laboratory Raman spectroscopy from process Raman spectroscopy: architecture, measurement accessibility, calibration, integration with DCS, and the financial model. A comparison from the perspective of a Polish manufacturer.

Review of new Raman publications from AGH, UJ/UJ CM, UW, PG and PW: MXene in Small 2026, Bi2Se3 in Photonics 2026, SERS in diabetes diagnostics, trends in ML and miniaturization — and what this implies for process applications.

Continuous monitoring of free phenol and formaldehyde in a PF resin reactor via inline Raman spectroscopy — how it eliminates analytical delay, reduces operator exposure, and enables real-time control of the condensation endpoint.

Raman Spectroscopy as a Process Analyzer in Chemistry — Selection of wavelength, probes, laser power, integration with DCS, and chemometric calibration.
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